API: Active pharmaceutical ingredient, any substance or mixture of substances intended to be used in the manufacture of a drug (medicinal) product and that, when used in the production of a drug, becomes an active ingredient of the drug product. Such substances are intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure and function of the body.We, Xi’an Wanlong Pharmaceutical Co., Ltd, produce 19 APIs at present, which include Dextran series(Iron Dextran 20% Solvent, Iron Dextran 10% Solvent, Dextran 1, Dextran 70, Dextran sulfate sodium salt, Iron dextran 30%, Iron dextran 38%, Dextran 40, Dextran 10, Dextran 5, Dextran 250 ), L-malic acid series(L-malic acid, L-malate sodium) and other APIs(Epalrestat, Moxonidine, Gadodiamide, Ubenimex, Tirofiban Hydrochloride, L-Alanyl-L-Glutamine).
Type： Dextran series: Dextran is a blood volume expanding drug, which can increase plasma colloid osmotic pressure, increase plasma volume and maintain blood pressure. It can prevent the aggregation of red blood cells and platelets, reduce blood viscosity, thereby improving the role of microcirculation. It is usually produced as an injection for patients to use. Iron dextran is an anti-anemia drug, which is a complex of dextran and iron. It is a soluble ferric iron agent, which can be made into injection for deep intramuscular injection for animals with severe iron deficiency anemia or intolerant or ineffective oral administration. It also can be made into tablets, granules, oral liquid for patients to use.
L-malic acid series: L-malic acid has a wide range of uses in medicine. Due to the special position of L-malic acid in the material metabolism pathway, it can directly participate in human metabolism and be directly absorbed by the human body to provide energy to the body in a short time, eliminate fatigue, and play the role of anti-fatigue and rapid recovery of physical strength. Health drinks can be developed by using the anti-fatigue, liver, kidney and heart protection functions of L-malic acid. The addition of L-malic acid to the drug can increase its stability and promote the absorption and diffusion of the drug in the human body. L-malic acid can also promote ammonia metabolism, reduce the blood ammonia concentration, and have a protective effect on the liver. It is a good medicine for the treatment of liver insufficiency, liver failure, liver cancer, especially hyperammonemia caused by liver dysfunction.
Other APIs: Epalrestat is an aldose reductase inhibitor. Moxonidine acts by stimulating central presynaptic α2-receptors and is used in essential hypertension. Gadodiamide is used as an MRI contrast agent. Ubenimex can enhance immune function and is used for adjuvant therapy of anti-cancer chemotherapy and radiotherapy, senile immunodeficienc，etc. Tirofiban hydrochloride, in combination with heparin, is suitable for patients with unstable angina pectoris or non-Q wave myocardial infarction prevent cardiac ischemic events, and also suitable for coronary angioplasty or intracoronary atherectomy in patients with coronary ischemic syndrome Internal atherectomy to prevent cardiac ischemic complications associated with sudden occlusion of treated coronary arteries. L-Alanyl-L-Glutamine is a dipeptide used as a glutamine substitute in mammalian cell culture media.