Ubenimex

Ubenimex

Synonyms: (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanoic acid
CAS No.
58970-76-6
Purity
98%~102%
Molecular Formula
C16H24N2O4
Therapeutic Category
protease inhibitor
Quality Standard
In-House(Tablet)
Documentations
GMP/DMF
Brand
Wanlong
Capacity
Commercially available


Description

Application

Ubenimex is an immunostimulant useful in the treatment of non-lymphocytic leukemia. In other types of cancers ubenimex added to radiotherapy or chemotherapy following surgery significantly inmases survival time through immunopotentiation.

Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Ubenimex competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Aminopeptidases has been implicated in the process of cell adhesion and invasion of tumor cells. Therefore, inhibiting aminopeptidases may partially attribute to the antitumor effect of ubenimex. This agent also activates T lymphocyte, macrophage and bone marrow stem cell as well as stimulates release of interleukin-1 and -2, thus further enhances its antitumor activity.

Appearance
White or almost white powder
Packaging
25g~1kg per to request.
Storage
Store in sealed containers and keep away from light
Shelf Life
36 months
Availability
In stock