Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose), originally derived from saccharose. IUPAC defines dextrans as "Branched poly-α-d-glucosides of microbial origin having glycosidic bonds predominantly C-1 → C-6".Dextran chains are of varying lengths (from 3 to 2000 kilodaltons).
Dextran 1 is composed of a small fraction (1 kilodalton) of the entire dextran complex. This is enough to bind anti-dextran antibodies, but insufficient to result in the formation of immune complexes and resultant immune responses. Thereby, dextran 1 binds up antibodies towards dextran without causing the immune response, leaving less antibodies left to bind to the entire dextran complex, causing less risk of an immune response upon subsequent administration of dextran.
All Pharmaceutical Quality Dextran manufactured by Wanlong meets the quality standards of the Pharmacopoeia. In all other aspects than molecular weight it is of the same chemical and biological purity and with specification limits analogous with the Pharmacopoeial products. Dextran 1 and Dextran 10 are selling to Europe and other areas, and the factory will receive 2 audits this month by customers and we welcome more customers to visit our factory.